Thank you Dr.Chaney for this great synopsis of the Vivix / Nrf2 study!!
http://www.shaklee.net/babyboomerhealth/product/AntiAging
Many of you have been asking when you will hear about Shaklee's clinical studies with Vivix. Your wait is over.
At their August 2009 global conference in St. Louis Missouri Shaklee released some results from one of their key clinical studies on Vivix.
This was a randomized, placebo controlled clinical study, the most rigorous kind of clinical study.
It was also an independent study performed not by Shaklee, but by scientists at State University of New York at Buffalo.
In short, this was the real deal!
In this study, a group of volunteers consumed a 910 calorie breakfast from Burger King. One half of the group took Vivix immediately after breakfast and the other half took a placebo.
For the group consuming Vivix a key genetic regulator of longevity called Nrf2 (pronounced Nerf 2) increased dramatically within the first 3 hours after the meal. For the placebo group Nrf2 levels actually declined.
If you are feeling a bit under whelmed at the moment, it's probably because this is the kind of study that needs a bit of additional explanation before you can fully appreciate it.
Let's start with the breakfast, which I have somewhat jokingly referred to as the "breakfast of champions".
You see that Burger King breakfast is loaded with the wrong kinds of fat - saturated fat & trans fat. That's the kind of fat that clogs your arteries.
Not only does it clog your arteries, but it also causes your arteries to contract dramatically right after the meal. If those arteries are already clogged from previous high fat meals...You guessed it...It can trigger a heart attack or stroke.
If you're lucky it could mean a trip to the emergency room. But, the most frequent symptom of heart disease is sudden death - often triggered by that fat laden "Happy Meal", If you'll pardon the mixed metaphor.
And it isn't just Burger King. Almost any fast food meal will do.
Now that I have your attention, let's talk about the protective effects of antioxidants.
In fact, you may have heard about previous clinical studies showing that supplementation with vitamin E or other antioxidants immediately after the "Happy Meal" can prevent that narrowing of the arteries and perhaps save you from that trip to the emergency room.
You might be asking "What does that have to do with Nrf2 and Vivix?" Be patient, I'm getting there.
You see when we are young, a "Happy Meal" will trigger an increase in Nrf2 which in turn increases production of our body's own antioxidant defense mechanisms.
Nrf2 also triggers our detoxification pathways so that we can get rid of all of the artificial food additives and preservatives in that "Happy Meal".
Nrf2 triggers our immune balance pathways (high fat meals depress the immune system and can also cause inflammatory and autoimmune responses).
Finally, Nrf2 triggers our anti-stress pathways (high fat meals trigger cortisol production, which can accelerate the aging process) and much, much more.
But when we get older, Nrf2 is no longer triggered by those high fat meals and we lose our natural protective mechanisms. When that happens the aging process, and our risk of heart attack or stroke, is increased by every high fat meal that we consume.
By now you are probably starting to understand why the ability of Vivix to activate the Nrf2 gene is such a big deal.
But, I don't want you to think of Vivix as simply an antidote to a bad diet. You see Vivix turns on Nrf2 whether you are consuming a high fat meal or not.
Just think how much more beneficial it will be to keep your natural antioxidant defense mechanisms, your detoxification systems, your immune system, and your anti-stress systems in tip top shape without wasting those resources having to compensate for the effects of a bad diet.
So let me summarize what this study shows:
- Vivix activates the Nrf2 gene, which is a master regulator of longevity.
- That shows that the dosage of resveratrol and ellagic acid in Vivix is appropriate, that those beneficial polyphenols get into your bloodstream (they are bioavailable) and that they have their intended anti- aging benefits.
- In short the study shows that Vivix works in real people like you & me.
- Nrf2, in turn, activates the body's antioxidant defense mechanisms, detoxification mechanisms, immune balancing mechanisms and anti-stress mechanisms. These are all mechanisms that slow down cellular aging and reduce the risk of degenerative diseases.
- Vivix can reduce the damage caused by a high fat diet, but will be even more effective at slowing the aging process if used along with a good diet and a lifestyle that includes weight control and exercise.
The study actually shows much more than this, but Shaklee can't release the other data until the manuscript has been accepted for publication. So stay tuned for even more exciting results in the future.
To your health!
Dr. Stephen Chaney, PhD
Shaklee Master Coordinator
Tuesday, August 11, 2009
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